RecruitingThrombocytopeniaNeonatalPlatelet Transfusion

Neonatal Platelet Transfusion Threshold Trial

Eligible age

All ages

Accepts

All genders

Locations

15 states

Healthy volunteers

Yes

See if you qualify for this study

Answer a few quick questions about your location and health. Takes about a minute.

Check my eligibility →

About this study

The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshold, improves survival without major or severe bleeding up to 40 0/7 weeks' postmenstrual age (PMA).

Sponsor: NICHD Neonatal Research Network

You may qualify if…

✓ Gestational age of 23 0/7 to 26 6/7 weeks
✓ Postnatal age of \< 48 hours

You may not qualify if…

✕ Comfort care or withdrawal of care planned
✕ Neonatal alloimmune thrombocytopenia or suspected/confirmed congenital platelet or bleeding disorder
✕ Receipt of platelet transfusion
✕ No receipt of Vitamin K
✕ Parents/guardian decline consent