RecruitingMenstrual Migraine

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

Eligible age

18–45 yrs

Accepts

Women

Locations

18 states

Healthy volunteers

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Answer a few quick questions about your location and health. Takes about a minute.

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About this study

The purpose of this study is to evaluate the efficacy and safety of rimegepant when administered during the peri-menstrual period (PMP) for intermittent prevention of migraine in women who experience menstrual migraine attacks.

Sponsor: Pfizer

You may qualify if…

✓ 1. Participant has regular menstrual cycles ≥24 days and ≤34 days
✓ 2. A minimum 1-year history of migraine (with or without aura) consistent with a diagnosis according to the International Classification of Headache Disorders, 3rd Edition
✓ 3. A history of menstrual migraine attacks of at least 3 months
✓ 4. Participant reported history of experiencing at least 1 migraine attack during the perimenstrual period in at least 2 out of 3 menstrual cycles immediately prior to screening.
✓ 5. If the participant is receiving a permitted background continuous prophylactic migraine medication, the medication dose must be stable for at least 3 months prior to the Screening visit and, the dose is not expected to change during the course of the study

You may not qualify if…

✕ 1. Greater than 6 migraine days per month that are outside of the perimenstrual period in the 3 months prior to Screening
✕ 2. A diagnosis of chronic migraine or a history of more than 14 headache days per month on average, in the 3 months prior to Screening
✕ 3. History of retinal migraine, basilar migraine or hemiplegic migraine
✕ 4. Current diagnosis of schizophrenia, bipolar, or borderline personality disorder
✕ 5. Other pain syndromes (eg, fibromyalgia, complex regional pain syndrome), or significant neurological disorders (other than migraine), or other medical conditions (including endocrine and gynecological eg, severe dysmenorrhea