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RecruitingNeoplasmsHPV-Related Anal Squamous Cell Carcinoma

Screening Strategies Among High-risk Populations for Anal Cancer

Eligible age

30–80 yrs

Accepts

All genders

Locations

2 states

Healthy volunteers

Yes

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About this study

The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.

Sponsor: Lisa Flowers

You may qualify if…

  • 30-80 years of age
  • Individuals with chronic impaired immune status
  • History of high-grade lower genital tract neoplasia (LGTN), Zubrod Performance Status of 0-2;

You may not qualify if…

  • Patients treated for aHSIL less than 6 months before screening,
  • History of anal cancer and pregnant women.

Where it's recruiting

Florida

Miami

Georgia

Atlanta

Source: ClinicalTrials.gov · NCT06628570 · last updated 2025-09-08

Screening Strategies Among High-risk Populations for Anal Cancer · TrialPath