RecruitingStrokeStroke, IschemicStroke Hemorrhagic
At-Home taVNS - Stroke Rehab
Eligible age
18–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
Early evidence suggests the benefits of post-stroke motor rehabilitation may be enhanced by applying electrical stimulation to the ear. This study aims to test the new approach of pairing ear stimulation with motor rehabilitation in the home setting in stroke survivors with upper limb motor function deficits.
Sponsor: Medical University of South Carolina
You may qualify if…
- ✓ 18-80 years old with an ischemic or hemorrhagic stroke that occurred ≥6 months prior;
- ✓ Ability to give consent;
- ✓ Unilateral limb (left or right) weakness with Fugl Meyer-Upper Extremity Scale score of 19-53/60 points which indicates adequate arm/hand use for rehabilitation tasks;
- ✓ active wrist flexion/extension ≥10° with active abduction/extension of thumb and at least 1 digit ≥10° to further assure ability to participate in rehabilitation tasks;
- ✓ Passive range of motion in affected shoulder, elbow and wrist within 20 degrees of normal values.
You may not qualify if…
- ✕ Other concomitant neurological disorders affecting upper extremity motor function;
- ✕ Presence of Dysphagia or aspiration difficulties;
- ✕ Prior injury to vagus nerve;
- ✕ Pregnancy;
- ✕ Documented history of dementia before or after stroke;
- ✕ Documented history of uncontrolled depression or psychiatric disorder either before or after stroke which could affect their ability to participate in the experiment;
- ✕ Uncontrolled hypertension;
- ✕ Botox injections within 4 weeks of the first day of rehabilitation therapy.
Where it's recruiting
South Carolina
Charleston
Source: ClinicalTrials.gov · NCT06616831 · last updated 2025-05-20