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RecruitingTobacco UseTobacco CessationInsomnia

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Eligible age

18–65 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.

Sponsor: Yale University

You may qualify if…

  • English literate
  • report heavy tobacco use (including nicotine e-cigarettes) for \>6 months
  • meet biochemical cut off for recent cigarette smoking or e-cigarette use
  • optimal body mass index

You may not qualify if…

  • currently enrolled in other treatments
  • neuropsychiatric exclusions that could interfere with study participation, increase risk of adverse events, and/or induce deficient sleep
  • medical contraindications for fMRI, varenicline, and/or behavioral treatment
  • factors that cause deficient sleep and for which behavioral treatment has less benefit
  • women who are pregnant or nursing

Where it's recruiting

Connecticut

New Haven

Source: ClinicalTrials.gov · NCT06609369 · last updated 2026-06-05