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RecruitingDepression

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression

Eligible age

18–64 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This is a pilot clinical trial to assess the feasibility, safety, and preliminary efficacy of ketamine-assisted group therapy for Spanish-speaking adults with depression

Sponsor: Juliana Zambrano, MD, MPH

You may qualify if…

  • ✓ 1\. Self-identifying Latinx, Spanish-speaking 2. Adults 18-64 years 3. Meet DSM-5 criteria for major depressive disorder as evaluated by study clinician 4. Montgomery-Asberg depression scale (MADRS) score of 20 or above at baseline 4. Participants must have an MGB psychiatrist and primary care provider.

You may not qualify if…

  • ✕ 1. History of primary psychotic disorder, by history
  • ✕ 2. History Bipolar I disorder, by history
  • ✕ 3. Unstable complex PTSD, as assessed by study clinician
  • ✕ 4. History of dissociative identity disorder
  • ✕ 5. History of neurocognitive disorder
  • ✕ 6. History of severe and/or recent substance use disorder, by history and as assessed by study clinician after clinical evaluation and interview
  • ✕ 7. Uncontrolled hypertension, tachycardia, or unstable cardiopulmonary disease, by history a. Blood pressure on initial screen must be \<140/90 mmHg.
  • ✕ 8. History of aortic dissection

Where it's recruiting

Source: ClinicalTrials.gov · NCT06597695 · last updated 2026-09-10