RecruitingObesityAdolescent ObesityBody-Weight Trajectory
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
Eligible age
12–24 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond weight loss alone. The study also plans to learn more about whether a medication (semaglutide or tirzepatide) can help people 12 to 24 years old who, between 6 and 24 months after bariatric surgery, have not lost as much weight as expected.
Sponsor: University of Colorado, Denver
You may qualify if…
- ✓ Signed and dated informed consent form
- ✓ Willingness to comply with all study procedures and availability for the duration of the study
- ✓ Male or female biological sex, age 12 through 24 years
- ✓ In the preoperative pathway for vertical sleeve gastrectomy
- ✓ Signed and dated informed consent form
- ✓ Status post vertical sleeve gastrectomy
- ✓ Male or female biological sex, age 12 through 24 years
- ✓ Meeting minimum nutrition goals
You may not qualify if…
- ✕ Planned Roux-en-Y gastric bypass
- ✕ Hypothalamic obesity
- ✕ Type 2 Diabetes
- ✕ Current use of oral glucocorticoids (i.e. within 10 days of baseline visit)
- ✕ Current use of insulin
- ✕ Intervention/Treatment Phase
- ✕ Surgically correctable cause of suboptimal postoperative weight loss
- ✕ Known hypersensitivity to any component of semaglutide
Where it's recruiting
Colorado
Aurora
Source: ClinicalTrials.gov · NCT06575738 · last updated 2026-07-15