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RecruitingGestational DiabetesObesityHealthy

Growth Hormone Resistance of Beta-cells A

Eligible age

18–45 yrs

Accepts

Women

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a personal history of gestational diabetes (high blood sugar in pregnancy) at the University of Missouri. The aim of the study is to advance understanding of how growth hormone affects beta-cells and risk factors for developing gestational diabetes.

Sponsor: University of Missouri-Columbia

You may qualify if…

  • Singleton, full term pregnancy within the past 5 years
  • Body mass index ≥18.5 kg/m2 and \<45.0 kg/m2
  • Group specific inclusion criteria:
  • Gestational Diabetes Group: History of gestational diabetes in the most recent pregnancy
  • Control Group: no history of gestational diabetes

You may not qualify if…

  • Pregnant, planning to become pregnant during the study, or breastfeeding
  • Current diagnosis or history of type 1 or type 2 diabetes
  • Use of medications that can impact the study outcomes (e.g., GLP-1 receptor agonists)
  • History of bariatric surgery
  • Known, uncontrolled hypothyroidism
  • History of intracranial hypertension, including papilledema, or a condition that increases the risk of developing intracranial hypertension, such as Turner Syndrome, Prader-Willi Syndrome, or renal impairment
  • Current cancer or cancer that has been in remission less than 5 years
  • First degree relative with diabetes diagnosis

Where it's recruiting

Missouri

Columbia

Source: ClinicalTrials.gov · NCT06571487 · last updated 2026-05-11

Growth Hormone Resistance of Beta-cells A · TrialPath