TBI Rehabilitation and Activation in Veterans
Eligible age
50–89 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This trial will evaluate the impact of a multicomponent program (TBI Rehabilitation and Activation in Veterans; TRAIN-Vets) on improving cognitive function over an 8-month trial period in older Veterans with traumatic brain injury (TBI). Older Veterans with a history of TBI and subjective cognitive complaints will be enrolled and randomly assign to either the TRAIN-Vets intervention (consisting of aquatic-based exercise training, cognitive training, and lifestyle coaching) or the Health Education Control, where they will receive educational materials about brain health and healthy lifestyles.
Sponsor: Northern California Institute of Research and Education
You may qualify if…
- ✓ Veteran, age 50-89 years
- ✓ History (more than 6 months post injury) of mild or moderate TBI defined by the Ohio State University TBI Identification Method and DOD/VA Clinical Practice Guidelines for Definition of TBI
- ✓ Sufficient vision and hearing to allow cognitive testing
- ✓ Willingness to participate in water-based exercise program + cognitive training program for eight months
- ✓ Approval of primary medical provider to participate in a water-based exercise program
- ✓ Subjective cognitive complaints as evidenced by self-report
- ✓ English proficiency to allow for cognitive testing
- ✓ Internet connected device to participate in testing and cognitive training
You may not qualify if…
- ✕ Current severe and unstable psychiatric disorder
- ✕ Diagnosis of dementia, Montreal Cognitive Assessment score less than 18, or delirium
- ✕ TBI within the past 6 months
- ✕ Acute illness or unstable chronic illness
- ✕ Current severe cardiac disease
- ✕ Severe TBI or open head injury
- ✕ Inability to exercise consistently
- ✕ Inability to read, verbalize understanding, and voluntarily sign the Informed Consent
Where it's recruiting
Palo Alto · San Francisco
Source: ClinicalTrials.gov · NCT06562127 · last updated 2025-05-16