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RecruitingResistant Hypertension

Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension

Eligible age

22–80 yrs

Accepts

All genders

Locations

5 states

Healthy volunteers

No

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About this study

HQ-HTN-G01 is a prospective, multicenter, single arm, open label, early feasibility study to evaluate initial safety and device design concept of "HyperQureTM RDN System", laparoscopic renal denervation therapy, in patients with resistant hypertension on three(3) or more antihypertensive medications

Sponsor: DeepQure Inc.

You may qualify if…

  • Subjects are eligible to participate if all of the following criteria are met:
  • 1. Aged ≥22 and ≤80 years old at time of enrollment (consent).
  • 2. Diagnosed with resistant hypertension.
  • 3. Office BP ≥140/90 mmHg at Screening Visit 1, and on at least 3 antihypertensive medications of different classes including a diuretic for at least 4 weeks prior to consent.
  • 4. Daytime ABP ≥135/85 mmHg after a four (4)-week run-in period at Screening Visit 2.
  • 5. Agrees to have all study procedures performed, and is competent and willing to provide written, informed consent to participate in this clinical study.

You may not qualify if…

  • Subjects are not eligible to participate if any of the following criteria are met:
  • 1. Has coverage diameter of renal artery less than 2 mm or greater than 11 mm.
  • 2. Has one or more of the following conditions:
  • 1. Unstable angina with stent implantation (percutaneous coronary intervention) within 3 months of enrolment.
  • 2. Myocardial infarction within 3 months of enrollment.
  • 3. Acute heart failure (New York Heart Association (NYHA) III-IV) within 3 months of enrollment
  • 4. Cerebrovascular accident or transient ischemic attack within 3 months of enrollment.
  • 5. Atrial fibrillation patients undergoing treatment and not in sinus rhythm. Notes: Patients who have received medical treatment, catheter or surgical treatment for atrial fibrillation and are in sinus rhythm are not excluded

Where it's recruiting

California

Orange · Stanford

Florida

Gainesville

Georgia

Atlanta

Michigan

Detroit

Minnesota

Rochester

Source: ClinicalTrials.gov · NCT06526858 · last updated 2026-08-10

Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Rena · TrialPath