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RecruitingEndometriosis

Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis

Eligible age

21+ yrs

Accepts

Women

Locations

1 state

Healthy volunteers

No

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About this study

Despite the proliferation of cannabis and cannabinoid products in recent years, little research has been done to determine the impact of these products on womens health conditions, including endometriosis. This study is designed to assess the impact of a custom-formulated, hemp-derived, full-spectrum, high-CBD product vs. placebo on clinical symptoms and biomarkers over the course of 12 weeks of treatment in patients with endometriosis. This project will provide information that does not currently exist on the potential efficacy of a cannabinoid-based sublingual product for endometriosis.

Sponsor: Mclean Hospital

You may qualify if…

  • 1. Subject has provided informed consent
  • 2. Sex assigned female at birth
  • 3. Subject is 21 or older
  • 4. Subject is fluent in English
  • 5. Subject endorses at least moderate levels of pain at the baseline visit
  • 6. Subject endorses having endometriosis

You may not qualify if…

  • 1. Non-fluent English speakers
  • 2. Endorsement of current substance use disorder, psychotic disorder, or an eating disorder
  • 3. Currently uses cannabis or cannabinoid products regularly
  • 4. Patients will be excluded if they have a positive urine pregnancy test, are trying to become pregnant, or are currently breastfeeding
  • 5. Presence of a serious or unstable medical illness, including liver, kidney, or cardiovascular disease (hyper/hypotension, cardiac disorders), or neurological disorder (including seizure disorder)
  • 6. Neuropathic pain or cancer-related pain
  • 7. Disclosure of a genetic polymorphism affecting CYP2C9 function

Where it's recruiting

Source: ClinicalTrials.gov · NCT06477406 · last updated 2026-03-30

Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis · TrialPath