International Care Bundle Evaluation in Cerebral Hemorrhage Research
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. Despite this, intensive care and neurosurgical interventions are uncommon. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowering, as well as the treatment of pyrexia and elevated blood glucose levels. The I-CATCHER team is now planning to conduct a similar study in Sweden and Australia, as well as in other high-income countries. The study has a clear focus on implementation, aiming to improve treatment and prognosis for patients with ICH within a few years. The purpose of I-CATCHER is to investigate whether a structured treatment package (Care Bundle) improves 3-month prognosis in patients with spontaneous ICH compared to standard care.
Sponsor: Region Skane
You may qualify if…
- ✓ Adults (age ≥18 years)
- ✓ Non-contrast computerized tomography (NCCT) imaging-verified diagnosis of spontaneous intracerebral haemorrhage
- ✓ ≤24 hours from symptom onset or presumed symptom onset (last seen well)
You may not qualify if…
- ✕ Previous care limitation
- ✕ End-stage comorbidity with short life-expectancy (\<6 m; e.g. terminal cancer)
- ✕ ICH caused by brain tumor or cerebral venous thrombosis
- ✕ Clinical signs of brain herniation at first presentation (unresponsive patient with bilaterally fixed, maximally dilated pupils)
- ✕ Pregnant women beyond 22 weeks gestation may only be included after thorough discussion with an obstetrician to determine risks vs benefit.
Where it's recruiting
Oklahoma City
Source: ClinicalTrials.gov · NCT06429332 · last updated 2026-05-22