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RecruitingSpinal Cord Injury

CE-STAND: Cervical Epidural STimulation After Neurologic Damage

Eligible age

22+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

CE-STAND aims to address three areas under-represented in research: chronic, cervical, and autonomic dysfunction. It is both significant and highly impactful, as treating autonomic dysfunction could substantially improve function and quality of life (QoL) in chronic cervical SCI patients.

Sponsor: University of Minnesota

You may qualify if…

  • ✓ Twenty two years of age or older
  • ✓ Able to undergo the informed consent/assent process
  • ✓ Stable, motor-complete SCI
  • ✓ Discrete SCI between C4 and C7 (upper extremity weakness)
  • ✓ ASIA A or B SCI Classification
  • ✓ Medically stable in the judgment of the PI
  • ✓ Intact segmental reflexes below the lesion of injury
  • ✓ Greater than 1 year since initial injury and at least 6 months from any required spinal instrumentation

You may not qualify if…

  • ✕ Diseases and conditions that would increase the morbidity and mortality of this surgery such as cardiopulmonary.
  • ✕ Individuals who require respiratory support, including ongoing or intermittent use of a ventilator and/or diaphragmatic pacer
  • ✕ Inability to withhold antiplatelet/anticoagulation agents perioperatively
  • ✕ Individuals who have history of recurrent autonomic dysreflexia in the judgment of the PI
  • ✕ Significant dysautonomia that would prohibit rehabilitation or any history of cerebrovascular accident or myocardial infarction associated with autonomic dysreflexia. A single tilt table test with syncope, presyncope, or SBP \< 50 or \> 200
  • ✕ Failure to exhibit cardiovascular autonomic dysfunction on tilt table testing
  • ✕ Other conditions that would make the subject unable to participate in testing/rehabilitation in the judgment of the PI
  • ✕ Patients who have participated in another study within the last 12 months in which they have received fluoroscopic or other related radiation exposure

Where it's recruiting

Minnesota

Minneapolis

Source: ClinicalTrials.gov · NCT06410001 · last updated 2026-03-27

CE-STAND: Cervical Epidural STimulation After Neurologic Damage · TrialPath