RecruitingHand Osteoarthritis
Metformin Treatment of Patients with Hand Osteoarthritis
Eligible age
18+ yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.
Sponsor: Marius Henriksen
You may qualify if…
- ✓ 1. Age ≥18 years
- ✓ 2. Hand OA according to the ACR criteria
- ✓ 3. Average finger (2 to 5) pain ≥4 on a 0-10 numeric rating scale (NRS where 10 is worst pain) over the past 30 days
- ✓ 4. Metformin naive
You may not qualify if…
- ✕ Comorbidities
- ✕ 1. History of, or current signs of medical disease that may affect joints, e.g. rheumatoid arthritis, gout, psoriatic arthritis
- ✕ 2. Psoriasis
- ✕ 3. Known malignancy (except successfully treated squamous or basal cell skin carcinoma)
- ✕ 4. Drug or alcohol abuse in the last year
- ✕ 5. Existing nerve entrapment syndromes (e.g. carpal tunnel syndrome)
- ✕ 6. Known diabetes
- ✕ 7. Generalised pain syndromes such as fibromyalgia
Source: ClinicalTrials.gov · NCT06367283 · last updated 2025-02-27