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RecruitingPreDiabetesHeart Rate Variability (HRV)Stress and Anxiety

Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial

Eligible age

25–64 yrs

Accepts

All genders

Locations

2 states

Healthy volunteers

No

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About this study

The goal of this randomized crossover trial is to compare the differences in psychological and physiological effects of walking in two different outdoor environments (urban/suburban commercial environments vs. urban/suburban nature areas/preserves) in adults with prediabetes. The main questions it aims to answer are: * Do psychological measures of stress, anxiety, and affect improve more in one type of outdoor environment over the other? * Do physiological measures of stress improve more in one type of outdoor environment over the other? As this is a crossover trial, participants will serve as their own controls. Researchers will compare both the psychological and physiological effects walking in the two types of outdoor environments. Participants will: * Walk 150-minutes per week for six weeks in each of the two outdoor conditions. * Visit the clinic four times, including before and after each six-week walking period. * Collect saliva samples immediately proceeding or following the four clinic visits. * Return to their pre-study level of physical activity for a 5-week washout period between each of the two walking interventions.

Sponsor: University of Minnesota

You may qualify if…

  • 25-64 years old.
  • Classified as overweight or obese with BMI 20.0-39.9 kg/m2 per self-report and a BMI of 20.0- 41.9 kg/m2 upon actual measure.
  • Documentation\* of a PreD diagnosis within one year of enrollment by physician or primary care provider based on lab tests showing a fasted blood glucose of 100-125 mg/dL, a 2-hour oral glucose tolerance test of 140-199 mg/dL, or an HbA1c level of 5.7%-6.49%271; OR a study screening lab value of HbA1C within the aforementioned range.
  • Currently engaged in ≤100 min/week of moderate to vigorous exercise -confirmed via a 7-day activity recall.
  • No exercise contraindications as assessed by the Physical Activity Readiness Questionnaire (PAR-Q) -this Questionnaire involves seven "yes" or "no" questions regarding an individual's health status. Answering "yes" to any one of these questions may require a prospective participant to acquire a written doctor's note stating they can safely participate in the trial's exercise intervention. The participant would not be enrolled until this doctor's note is received.
  • Stable weight over the last 3 months (less than 10% change).
  • Not currently pregnant, planning to become pregnant, or currently breastfeeding.
  • Willing to maintain current dietary and exercise habits, aside from any changes to be made per the study exercise protocol.

You may not qualify if…

  • Individuals \<25 or \>64: younger individuals may have not yet reached physiological maturity and in whom PreD prevalence is low; older individuals are more likely to have contraindications to PA and other comorbidities.
  • BMI \<20 or ≥42.
  • Individuals with an HbA1c level \<5.7% or \>6.4%.
  • Currently engaged in \>100 min/wk of PA.
  • Individuals with contraindications to exercise participation as indicated by the PAR-Q.
  • A self-reported physical/mental disability that would prevent them from being able to adhere to the intervention.
  • Past or current diagnosis of Diabetes (Type 1, 1.5 or 2) or use of diabetic medications (e.g. medications to control blood sugar)
  • Any history of a cardiovascular disease event (e.g. heart attack, ablation, pacemaker, stroke)

Where it's recruiting

Illinois

Lake Forest · Winfield

Minnesota

Minneapolis

Source: ClinicalTrials.gov · NCT06365723 · last updated 2026-06-18

Effects of Walking in Greenspace and the Built Environment in Adults W · TrialPath