RecruitingChronic PainChronic InsomniaOpioid Use

Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.

Sponsor: University of South Florida

You may qualify if…

✓ 18+ yrs
✓ willing to be randomized,
✓ can read/understand English
✓ diagnosed with chronic widespread pain and insomnia (as described below)
✓ prescribed opioid medication for 1+ mo, 3+ times per week
✓ desire to reduce or eliminate opioid use
✓ written agreement from physician prescribing opioid medication
✓ no prescribed or OTC sleep meds for 1+ mo, or stabilized on meds for 6+ wks

You may not qualify if…

✕ unable to provide informed consent
✕ cognitive impairment (MMSE \<26)
✕ sleep disorder other than insomnia \[i.e., sleep apnea (apnea/hypopnea index, AHI \>15)
✕ Periodic Limb Movement Disorder (myoclonus arousals per hour \>15)\]
✕ bipolar or seizure disorder (due to risk of sleep restriction treatment)
✕ other severe, untreated major psychopathology except for depression or anxiety (e.g.,suicidal ideation/intent, psychotic disorders)
✕ psychotropic or other medications (e.g., beta-blockers) that alter pain or sleep (medications prescribed for pain or sleep are allowed)
✕ participation in other non-pharmacological treatment for pain, sleep, or mood outside the current trial

Where it's recruiting

Florida

Tampa

Source: ClinicalTrials.gov · NCT06345872 · last updated 2026-04-21