A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Eligible age
18–80 yrs
Accepts
All genders
Locations
31 states
Healthy volunteers
No
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About this study
The study will assess the efficacy and safety of 2 dose regimens of pegozafermin compared to placebo for the treatment of liver fibrosis stage F2 or F3 in adult participants with MASH.
Sponsor: 89bio, Inc.
Where it's recruiting
Birmingham
Chandler · Flagstaff · Glendale · Tucson
Conway · Little Rock · North Little Rock
Canoga Park · Coronado · Escondido · Fountain Valley …
Colorado Springs · Littleton
Brandon · Clermont · Fort Myers · Hialeah Gardens …
Athens · Dalton · Marietta
Chicago
Hammond · New Albany · South Bend
Iowa City
Topeka
Covington · Houma · Lake Charles · Marrero …
Source: ClinicalTrials.gov · NCT06318169 · last updated 2026-06-04