Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery
Eligible age
18+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
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About this study
This phase II trial evaluates manual lymphatic drainage breast massage for reducing treatment-related side effects in women undergoing radiation therapy after breast conserving surgery for breast cancer that has not spread to other parts of the body (localized). Breast conserving surgery can be an effective treatment option for early stage breast cancer, but it can also be associated with side effects including fluid collection in tissues/swelling (lymphedema), pain, reduced quality of life, and poorer body image. Manual lymphatic drainage is a gentle massage technique used to reduce swelling. It may be a safe and effective way to reduce treatment-related side effects in women receiving radiation therapy after surgery for localized breast cancer.
Sponsor: University of Southern California
You may qualify if…
- ✓ Female with native breasts and localized breast cancer who are status post-lumpectomy surgery, will receive whole breast radiation therapy with/without nodal irradiation, with standard fractionation or moderate hypofractionation
- ✓ Age \>= 18 years
- ✓ Ability to understand and the willingness to sign a written informed consent in English or Spanish
You may not qualify if…
- ✕ Underlying diagnosis of chronic inflammatory illness or collagen vascular disorder, e.g. scleroderma, lupus, rheumatoid arthritis, fibromyalgia as these conditions may significantly affect the likelihood and magnitude of radiation related toxicity
- ✕ Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, unstable cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
- ✕ Inability to provide written informed consent in English or Spanish
- ✕ Patients receiving ultra-hypofractionation, and/or partial breast or chest wall radiation therapy are excluded
Where it's recruiting
Los Angeles
Source: ClinicalTrials.gov · NCT06297265 · last updated 2026-06-05