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RecruitingPost Acute Sequelae of SARS CoV 2 InfectionObstructive Sleep Apnea

Predictors of Post-COVID-19 Clinical and Cognitive Consequences

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients. These sequelae may be present four or more weeks after SARS-COV-2 infection, including patients who had initial mild or asymptomatic acute infection. However, there is complete absence of data whether chronic sleep changes due to COVID-19 infection may influence these physical and mental health consequences. While fatigue is one of the common post-COVID conditions, there are no systematic examinations of sleep disturbances in COVID-19 survivors. This will be a pilot observational retrospective and prospective cohort study, to systematically assess if sleep disturbances and severity of sleep apnea comprise a modifiable facet of PASC as well as the short-term and longer-term effects of COVID-19 infection itself on sleep, cognitive function, exercise capacity and lung function.

Sponsor: VA Office of Research and Development

You may qualify if…

  • All individuals 18 years or older, with prior history of COVID-19 infection diagnosis
  • Both genders including all racial and ethnic groups
  • Patients with OSA (apnea hypopnea index of 5/hour on polysomnography) with history of COVID-19 infection will be eligible with prior history of COVID-19 infection and without COVID-19 for Aim 2

You may not qualify if…

  • Inability to give consent
  • Active suicidal symptoms
  • Children of all ages
  • Pregnant women

Where it's recruiting

Michigan

Detroit

Source: ClinicalTrials.gov · NCT06291870 · last updated 2026-01-23

Predictors of Post-COVID-19 Clinical and Cognitive Consequences · TrialPath