TTrialPathMatch Me to Trials
← Back to trials
RecruitingOsteo Arthritis KneeArthritis

Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

Eligible age

50–85 yrs

Accepts

All genders

Locations

2 states

Healthy volunteers

Yes

See if you qualify for this study

Answer a few quick questions about your location and health. Takes about a minute.

Check my eligibility →

About this study

The purpose of this study is to assess the ability of long-duration low intensity therapeutic ultrasound (LITUS) to alleviate knee Osteoarthritis pain over a 24-week period. The primary objective of this study is to evaluate the analgesic effect of LITUS in subjects suffering from knee Osteoarthritis pain. Secondary objectives are to assess the ability of LITUS to improve joint function.

Sponsor: ZetrOZ, Inc.

You may qualify if…

  • ✓ Have physician-diagnosed mild to moderate knee OA (OARSI atlas grades 1-2)
  • ✓ Fulfill the American College of Rheumatology clinical and radiological diagnostic criteria for knee OA
  • ✓ Are between 50-85 years of age
  • ✓ Report a frequent pain score between 4-7 (range: 0-10) during the week preceding enrollment
  • ✓ Report that knee pain negatively affects quality of life
  • ✓ Are willing not to use any cream, gel, or topical solution during the administration of treatment other than the approved ultrasound gel provided to the subject at the initiation of the study
  • ✓ Are deemed appropriate by their physician or by the study site physician to participate.
  • ✓ Be willing and able to self-administer treatment daily within their place of residence or during normal daily activity, excluding bathing, showering, or other water activities which may result in submersion of the study device.

You may not qualify if…

  • ✕ Cannot successfully demonstrate the ability to put on and take off the device.
  • ✕ Displays any condition which, in the judgment of the investigator, would make participation in the study unacceptable including, but not limited to, the subject's ability to understand and follow instructions.
  • ✕ Participated in a clinical trial for an investigational drug and/or agent within 30 days prior to screening.
  • ✕ Is pregnant.
  • ✕ Is a prisoner.
  • ✕ Is non-ambulatory (unable to walk).
  • ✕ Has a pacemaker.
  • ✕ Has a malignancy in the treatment area.

Where it's recruiting

Connecticut

Stamford · Trumbull

New York

Dryden

Source: ClinicalTrials.gov · NCT06257537 · last updated 2025-03-06