Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
Eligible age
18–45 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity. Participants will undergo a randomized controlled trial, with sleep extension (intervention) and healthy lifestyle (control) groups. The sleep extension is designed to increase participant's time in bed by 2 hours per night. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).
Sponsor: University of Utah
You may qualify if…
- ✓ 1. Age: 18-45 years old; equal numbers of men and women
- ✓ 2. Body mass index (BMI): 27.5-34.9 kg/m2
- ✓ 3. Sleep Habits: habitual self-reported average total sleep time (TST) \<6.5 hours per night for prior 6 months
You may not qualify if…
- ✕ 1. Clinically diagnosed sleep disorder or major psychiatric illness
- ✕ 2. Evidence of significant organ dysfunction or disease (e.g., heart disease, kidney disease)
- ✕ 3. Clinically diagnosed diabetes or fasting plasma glucose ≥126 mg/dL or HbA1c ≥6.5%
- ✕ 4. Use of prescription drugs or substances known to influence sleep or glucose metabolism, or anticoagulant medications.
- ✕ 5. Cancer that has been in remission less than 5 years
- ✕ 6. Pregnant/nursing, experiencing menopause or post-menopausal
- ✕ 7. Shift-work: current or history of within last year
- ✕ 8. Weight change: \>10% of body weight over prior six months
Where it's recruiting
Salt Lake City
Source: ClinicalTrials.gov · NCT06180837 · last updated 2024-12-20