RecruitingHead and Neck Squamous Cell Carcinoma

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

Eligible age

18+ yrs

Accepts

All genders

Locations

16 states

Healthy volunteers

See if you qualify for this study

Answer a few quick questions about your location and health. Takes about a minute.

Check my eligibility →

About this study

The study is a prospective, longitudinal, non-interventional, multicenter study of participants with HNSCC who will have tissue and blood based molecular biomarker profiling during their standard of care treatment.

Sponsor: Tempus AI

You may qualify if…

✓ ≥18 years of age
✓ Willing and able to provide informed consent
✓ Histologically- or cytologically-confirmed metastatic or unresectable, recurrent HNSCC unsuitable for local therapies
✓ Intended for first line anti-PD1 or PDL1 monotherapy or combination therapy
✓ Must submit tumor tissue sample representative of current disease per laboratory manual

You may not qualify if…

✕ Non-squamous histologies (eg, nasopharynx or salivary gland)
✕ Relapse or recurrence within 6 months of first line chemotherapy and / or chemoradiotherapy
✕ Tumors that are PD-L1 negative (CPS \<1)
✕ Clinical evidence of an active second invasive malignancy within \<2 years of enrollment with the exception of stable prostate cancer on watchful waiting, in situ cervical cancer, in situ breast carcinoma or localized non-melanoma skin cancers
✕ Unable to comply with study procedures (i.e., not willing or able to have additional blood samples collected)