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RecruitingCirrhosis, LiverEnd Stage Liver DIseaseSymptoms and Signs

Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease

Eligible age

18+ yrs

Accepts

All genders

Locations

2 states

Healthy volunteers

No

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About this study

Remote healthcare monitoring for cirrhosis has shown promise in overcoming barriers to accessing specialty care, improving healthcare quality, and reducing mortality. The LiverWatch study is investigating whether a remote nutrition, physical activity, and education intervention can improve health outcomes in those with cirrhosis. In this clinical trial, individuals will be randomized to either enhanced usual care or the LiverWatch intervention. Both groups are given fitbits and asked to increase their step counts. Those in the Liverwatch group will be incentivized for increase their physical activity while also undergoing a personalized nutrition intervention and weekly symptom monitoring and cirrhosis education.

Sponsor: University of Pennsylvania

You may qualify if…

  • English speaking
  • Aged 18 years or older
  • Home-dwelling
  • Diagnosis of cirrhosis- Child Turcotte-Pugh (CTP) B or C or a complication in the past 6 months (CTP B or higher, hepatic encephalopathy, variceal bleeding, fluid overload, liver-related hospitalization, or requiring symptom management with diuretics, non-absorbable disaccharides, rifaximin, nonselective beta blockers)
  • Patient and/or caregiver is able and willing to receive SMS text messages
  • Willing and able to wear personal fitness trackers and engage with study staff

You may not qualify if…

  • No access to a smartphone
  • Non-home dwelling
  • On hospice care
  • Model for end stage liver disease (MELD) score ≥30
  • Advanced hepatocellular carcinoma, BCLC C or higher
  • Hospitalization within the last 30 days
  • Deemed not appropriate by treating physician for medical reasons
  • Enrolled in other dietary or physical activity interventions

Where it's recruiting

Michigan

Ann Arbor

Pennsylvania

Philadelphia

Source: ClinicalTrials.gov · NCT06136221 · last updated 2026-05-11