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RecruitingAppetitive BehaviorObesity

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Eligible age

18–65 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about the role of the cerebellum in satiety.

Sponsor: Brigham and Women's Hospital

You may qualify if…

  • Healthy individuals aged 18 to 65
  • BMI of 20-35.0 kg/m2
  • Normal or corrected-to-normal vision
  • Good general health
  • Ability to understand and willingness to sign written informed consent document

You may not qualify if…

  • Current and/or past medical conditions
  • Current and/or past eating disorder
  • On a restricted diet and/or taking weight loss medication(s)
  • History of bariatric surgery
  • Weight fluctuation \>3% in past 3 months
  • Recent history of illicit recreational drug abuse
  • Current nicotine use
  • Intellectual disability

Where it's recruiting

Massachusetts

Belmont · Boston

Source: ClinicalTrials.gov · NCT06105164 · last updated 2025-12-05

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans · TrialPath