ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery
Eligible age
18–70 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
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About this study
Breast cancer is the second most common cancer diagnosed in American women . For patients who have undergone surgical mastectomy, autologous breast reconstruction is an alternative option to breast implants. Deep Inferior Epigastric Perforator (DIEP) flaps are the gold standard for autologous breast reconstruction . Effective pain control following surgery is imperative and ultrasound-guided bilateral transversus abdominis plane blocks (TAPs) with the infiltration of local anesthetics, such a ropivacaine are a common regional technique of choice . A newer described technique, bilateral Erector Spinae Plane blocks (ESPBs) (which also are an infiltration of local anesthetic) present as an alternative approach for post-operative analgesia. ESPBs have been proven efficacious in reducing intra- and post-operative opioid requirements, lessening the need for rescue analgesics in other similar surgical procedures. The hypothesis is that preoperative bilateral ESPBs could provide equivalent pain control as a regional analgesic for patients undergoing DIEP flap surgery when compared to preoperative bilateral TAPs
Sponsor: University of Kansas Medical Center
You may qualify if…
- ✓ Adult women with breast cancer, ASA 1-3, undergoing DIEP flap surgery
You may not qualify if…
- ✕ Chronic opioid use contraindications to local anesthetics or regional analgesia Inability to communicate intensity of pain on a numeric analog scale
Where it's recruiting
Kansas City
Source: ClinicalTrials.gov · NCT06091241 · last updated 2026-06-04