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RecruitingOsteoarthritis, Knee

Effect of Anti-inflammatory Diet in Osteoarthritis

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with Osteoarthritis, and the role of microbiome and circulating metabolites.

Sponsor: University of California, San Diego

You may qualify if…

  • Unilateral radiographic symptomatic KOA
  • No changes in therapy during the previous 3 months
  • Interested in dietary intervention and able to provide consent and attend follow-up visits

You may not qualify if…

  • Previous knee surgery
  • Severe radiographic disease (KL grade 4)
  • Rheumatoid Arthritis
  • Any Abnormal blood values in the comprehensive metabolic panel test at screen (Abnormality will be defined based on standard reference ranges)
  • Use of corticosteroids and/or intra-articular injections during the preceding 3 months
  • Use of fish oils and glucosamine
  • Participation in a weight loss program in the preceding 6 months
  • Recent changes in physical activity levels

Where it's recruiting

California

San Diego

Source: ClinicalTrials.gov · NCT06080347 · last updated 2024-11-04

Effect of Anti-inflammatory Diet in Osteoarthritis · TrialPath