RecruitingMigraine
Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Eligible age
18–85 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
Sponsor: Texas Tech University Health Sciences Center, El Paso
You may qualify if…
- ✓ Meet ICHD-3 Migraine Headache Criteria
- ✓ Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2
- ✓ Nerve block performed with bupivacaine 0.5%
You may not qualify if…
- ✕ Head trauma
- ✕ Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma)
- ✕ Headache in the setting of viral syndrome
- ✕ Chronically on steroids
- ✕ Known allergy to dexamethasone
- ✕ Unable to reach the patient by phone or text for follow-up
- ✕ Gestational diabetes or other uncontrolled diabetes
- ✕ Known to be immunocompromised
Where it's recruiting
Texas
El Paso
Source: ClinicalTrials.gov · NCT06016465 · last updated 2026-05-06