Goal Setting to Promote Physical Activity Adherence in Midlife Adults
Eligible age
45–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
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About this study
Engaging in regular physical activity during midlife is a key lifestyle behavior associated with reduced risk for Alzheimer's disease and related dementias (AD/ADRD). Yet nearly half of midlife adults (48%) do not meet national physical activity guidelines. The purpose of this mechanistic trial is to identify effective goal setting techniques to enhance psychosocial processes of self-regulation for the successful promotion of PA and adherence to national PA guidelines among midlife adults, with the long-term goal of reducing AD/ADRD risk
Sponsor: Arizona State University
You may qualify if…
- ✓ Aged 45 to 65 years
- ✓ BMI between 30 kg/m2 to 50 kg/m2
- ✓ Participants must weigh a minimum of 110 pounds
- ✓ Engaging in 60 minutes or less of self-reported moderate-to-vigorous physical activity at screening (based on Exercise Vital Sign Questionnaire)
- ✓ Self-reported ownership of a smartphone with an iOS or Android operating system (necessary for participants to track their activity using a Fitbit activity monitor)
You may not qualify if…
- ✕ Endorsing an item on the Physical Activity Readiness Questionnaire (PAR-Q), unless a physician's note is provided
- ✕ Resting blood pressure greater than 200/110 mmHG as assessed at the baseline study assessment (unless a physician's note is provided)
- ✕ Pregnant or planning to become pregnant in next 8-months (Phase 1) or 12 months (Phase 2)
- ✕ Plans to relocate out of metropolitan Phoenix, Arizona area in the next 8-months (Phase 1) or 12 months (Phase 2)
- ✕ Participation in another physical activity, nutrition or weight loss program at time of screening or at any time during the intervention
- ✕ Individuals with mild cognitive impairment (MCI), as determined by either a self-report of receiving a diagnosis of MCI from a health care provider or as assessed by the Montreal Cognitive Assessment (MoCA) at the study orientation session. A score \< 26 is an exclusion criterion for US born participants. A score of \<23 is an exclusion for participants born outside of the US who completed their high school education in a country where English is not the primary language.
- ✕ Being previously prescribed one of the 5 approved Alzheimer's medications, including: Donepezil (Aricept), Rivastigmine (Exelon), Galantamine (Razadyne), Memantine (Namenda), Memantine + Donepezil (Namzaric)
- ✕ Score of 16 or higher on the Center for Epidemiological Studies-Depression Scale (CES-D)
Where it's recruiting
Phoenix
Source: ClinicalTrials.gov · NCT05980052 · last updated 2026-07-17