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RecruitingDementiaAlzheimer DiseaseInfections

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

Eligible age

60–106 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.

Sponsor: Hebrew SeniorLife

You may qualify if…

  • 1. Age \> 60
  • 2. A diagnosis of dementia (any type)
  • 3. Cognitive Functional Scale (CFS) \> 1
  • 4. NH length of stay \>90 days
  • The CFS score categorizes cognitive impairment status based on data in the electronic health record into: 1. None, 2. Mild, 3. Moderate, and 4. Severe (advanced). For the primary outcome, the analysis will be restricted to residents with a CFS score of 3 or 4.

You may not qualify if…

  • 1. Less than 60 years of age
  • 2. Living in nursing home for less than 90 days
  • 3. Does not have diagnosis of dementia
  • 4. Does not meet CFS \>1 score

Where it's recruiting

Source: ClinicalTrials.gov · NCT05950607 · last updated 2026-01-06

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzhe · TrialPath