RecruitingObsessive-Compulsive Disorder
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
Eligible age
18–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
The purpose of this study is to understand how ketamine works in the brain to bring about a reduction in OCD symptoms.
Sponsor: Stanford University
You may qualify if…
- ✓ Ages 18-65
- ✓ Meet the criteria for OCD diagnosis
- ✓ Failed at least 1 prior trial of standard first-line OCD treatment
- ✓ Agree to the following lifestyle modifications: comply with requirements for fasting prior to the Experimental Session, not enroll in any other interventional clinical trials during the duration of the study, and commit to medication study procedures.
- ✓ Able to provide informed consent
- ✓ Ages 18-65
- ✓ Able to provide informed consent
You may not qualify if…
- ✕ prior naltrexone or ketamine use/exposure
- ✕ Any current or past medical/psychiatric condition that makes participation unsafe in the opinion of the investigator or study physician
- ✕ Pregnant or nursing, or able to become pregnant and are not practicing an effective means of birth control
- ✕ the presence of metal in the body that is contraindicated for MRI scans
- ✕ Eligibility Criteria for Healthy Volunteers:
- ✕ current or past use of psychotropic medication
- ✕ pregnant or nursing females
- ✕ the presence of metal in the body that is contraindicated for MRI scans
Where it's recruiting
California
Stanford
Source: ClinicalTrials.gov · NCT05940324 · last updated 2026-04-24