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RecruitingPrader-Willi Syndrome

Cerebellar TMS and Satiety in Prader-Willi Syndrome

Eligible age

18–64 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study hyperphagia and satiety in Prader-Willi syndrome. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about how TMS might improve hyperphagia in Prader-Willi syndrome.

Sponsor: Brigham and Women's Hospital

You may qualify if…

  • ✓ Diagnosis of Prader-Willi syndrome

You may not qualify if…

  • ✕ contraindications for TMS or MRI including :
  • ✕ history of neurological disorder
  • ✕ history of head trauma resulting in loss of consciousness
  • ✕ history of seizures or diagnosis of epilepsy or first degree relative family history of epilepsy
  • ✕ metal in brain or skull
  • ✕ implanted devices such as a pacemaker, medication pump, nerve stimulator or ventriculoperitoneal shunt claustrophobic in MRI

Where it's recruiting

Source: ClinicalTrials.gov · NCT05938543 · last updated 2025-12-05

Cerebellar TMS and Satiety in Prader-Willi Syndrome · TrialPath