Gastroparesis Registry 4
Eligible age
18–85 yrs
Accepts
All genders
Locations
6 states
Healthy volunteers
No
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About this study
The Gastroparesis Registry 4 (GpR4) is an observational study of patients with symptoms of gastroparesis (Gp) and functional dyspepsia (FD) with either delayed or normal gastric emptying. To better understand these disorders, this registry will capture demographic, clinical, physiological, questionnaire, and patient outcome data to characterize the patients and their clinical course. Participants will complete several questionnaires, complete a nutrient drink test and have a gastric emptying study.
Sponsor: Johns Hopkins Bloomberg School of Public Health
You may qualify if…
- ✓ Age at least 18 years at initial screening visit
- ✓ Symptoms of Gp and/or FD of at least 12-weeks duration with varying degrees of nausea, vomiting, early satiety, postprandial fullness, abdominal pain, abdominal burning. Thus, patients can enter the GpR4 registry primarily with abdominal pain suggesting FD-Epigastric Pain Syndrome.
- ✓ Successful completion of gastric emptying scintigraphy of solids using the 4-hour Egg Beaters® protocol (or equivalent generic liquid egg white meal) within the last 9 months
- ✓ Negative upper endoscopy or upper radiographic GI series within 5 years of registration
You may not qualify if…
- ✕ Use of narcotic analgesics greater than three days per week
- ✕ Presence of other conditions that could explain the patient's symptoms such as:
- ✕ Pyloric or intestinal obstruction as evidenced by EGD, UGI, or Abdominal CT
- ✕ Active inflammatory bowel disease
- ✕ Known eosinophilic gastroenteritis or eosinophilic esophagitis
- ✕ Primary neurological conditions that can cause nausea and vomiting such as increased intracranial pressure, space occupying or inflammatory/infectious lesions
- ✕ Acute or chronic renal failure (serum creatinine \>3 mg/dL) and/or on hemodialysis or peritoneal dialysis
- ✕ Acute liver failure or advanced liver disease (Child's B or C; a Child-Pugh-Turcotte (CPT) score of ≥7)
Where it's recruiting
Scottsdale
Louisville
Boston
Charlotte
Philadelphia
El Paso
Source: ClinicalTrials.gov · NCT05846802 · last updated 2026-04-03