RecruitingBacterial VaginosisVulvovaginal Candidiasis
Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome
Eligible age
18–54 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
This project aims to investigate if the contraceptive method, Phexxi, causes changes to the composition of the vaginal microbiome. The investigators hypothesize that regular use of Phexxi will cause increased colonization of lactic acid-producing lactobacilli, which could have positive effects in the way of preventing recurrent episodes of BV and candida infections.
Sponsor: Queen's Medical Center
You may qualify if…
- ✓ Age 18-54
- ✓ Female
- ✓ Pre-menopausal
- ✓ Can speak and read in English
- ✓ Displays capacity for informed consent
- ✓ Has had 2 or more documented and/or self-reported episodes of symptomatic BV or candida infection in the last year, requiring, over-the-counter or prescription treatment
You may not qualify if…
- ✕ Pregnant or trying to become pregnant
- ✕ Post-menopausal
- ✕ Using NuvaRing device
- ✕ A past medical history of kidney disease, recurrent UTI, and/or urinary tract abnormalities
- ✕ Current UTI
- ✕ Using Phexxi as a contraceptive during the collection period of the study
Where it's recruiting
Hawaii
Honolulu
Source: ClinicalTrials.gov · NCT05753813 · last updated 2026-02-20