RecruitingAlzheimer Disease
Autologous Activated Adipose-derived Stem Cells (RB-ADSC) Injected Directly Into the Brain for Mild to Moderate Alzheimer's Disease
Eligible age
45–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
This is a research study to evaluate the safety of an investigational autologous cell product obtained from participant's own adipose tissue as a possible treatment for Alzheimer disease.
Sponsor: Regeneration Biomedical, Inc.
You may qualify if…
- ✓ ≥45 and ≤80 years of age
- ✓ Mild to moderate AD diagnosis
- ✓ Adequate cognitive function
- ✓ Non-remarkable clinical laboratory
- ✓ Ability to voluntarily provide written informed consent
- ✓ No tumors or other disease responsible for dementia
- ✓ Well-controlled comorbidities, on stable medications for 3 months
- ✓ The participant is otherwise in good general health
You may not qualify if…
- ✕ Taking other medications for AD, except that donepezil memantine, AChEIs including patches, Vitamin E, fish oil, and/or gingko biloba are allowed if doses have been stable for at least 3 months prior to the Screening visit
- ✕ Stem cell implantation of any type within 3 months
- ✕ Existing ventriculoperitoneal shunts
- ✕ Neurological disorders except AD
- ✕ Psychiatric disorders including schizophrenia, bipolar/unipolar depressive disorder, delirium
- ✕ Drug or alcohol abuse or dependence within the past 5 years
- ✕ Participants with a history of cancer in the past 5 years
- ✕ No caregiver available to meet the inclusion criteria for caregivers
Where it's recruiting
California
Newport Beach
Source: ClinicalTrials.gov · NCT05667649 · last updated 2025-04-04