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RecruitingLiver Disease; Alcohol-RelatedCirrhosisAlcohol Use Disorder

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The purpose of this research study is to test the safety, tolerability, and effectiveness of the capsules that contain bacteria from healthy individuals when used to treat alcohol craving and drinking.

Sponsor: Virginia Commonwealth University

You may qualify if…

  • \>18 years of age
  • Advanced liver disease
  • Able to give written, informed consent
  • Alcohol as a cause of advanced liver disease
  • Continued sustained drinking
  • Having previously declined a referral to traditional AUD therapy services or having failed such treatments

You may not qualify if…

  • Lack of sustained drinking
  • Recent or current alcoholic hepatitis
  • Alcohol withdrawal symptoms
  • Clinically significant use of illicit drugs
  • Uncontrolled mood disorders or primary psychotic conditions
  • MELD score\>17
  • Unclear diagnosis of chronic liver disease
  • Current hepatic encephalopathy on lactulose and/or rifaximin

Where it's recruiting

Virginia

Richmond

Source: ClinicalTrials.gov · NCT05548452 · last updated 2026-07-14

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease · TrialPath