RecruitingEndometriosis
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
Eligible age
18–55 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Purpose: The aim of this study is to assess the sensitivity and specificity of FFNP PET/MRI for diagnosis of endometriosis. Participants: A total of 24 participants will be recruited from individuals with clinically suspected endometriosis. Procedures (methods): This is a prospective, one arm, single center study of 24 subjects with clinically suspected endometriosis to demonstrate FFNP PET-MRI's clinical utility for diagnosis of endometriosis.
Sponsor: University of North Carolina, Chapel Hill
You may qualify if…
- ✓ Age 18 or older
- ✓ Female of childbearing age (18-55 years)
- ✓ Clinically suspected (symptomatic) endometriosis as defined by referring physician (this would also include endometriomas as other disease may be present).
- ✓ Scheduled for planned operative laparoscopy with no hormone treatment for at least two cycles
- ✓ Able to provide informed consent
You may not qualify if…
- ✕ Male
- ✕ Institutionalized subject (prisoner or nursing home patient)
- ✕ Known history of breast, ovarian or endometrial cancer.
- ✕ Pregnant or breast-feeding women
- ✕ Chronic progestin-containing medications or Gonadotropin-releasing hormone (GnRH) analogues in the last 10-16 days (or 2 cycles in the case of GnRH analogues as these are dosed monthly) or inability to discontinue these medications
- ✕ Allergy to gadolinium contrast or Glomerular Filtration Rate (GFR) below 30 ml/min.
Where it's recruiting
North Carolina
Chapel Hill
Source: ClinicalTrials.gov · NCT05480995 · last updated 2026-01-12