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RecruitingNon Small Cell Lung CancerPancreatic Ductal Adenocarcinoma

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

Eligible age

18+ yrs

Accepts

All genders

Locations

5 states

Healthy volunteers

No

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About this study

This is a first-in-human, Phase 1/2, open-label, study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of Mavrostobart (PT199) alone and in combination with a PD-1 inhibitor or chemotherapy.

Sponsor: Phanes Therapeutics

Where it's recruiting

North Carolina

Huntersville

Oklahoma

Oklahoma City

Tennessee

Nashville

Texas

Houston · Webster

Virginia

Fairfax

Source: ClinicalTrials.gov · NCT05431270 · last updated 2026-05-19