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RecruitingSleepInsomniaSleep Deprivation

The Effect of Sleep Loss on Emotion Regulation

Eligible age

18–40 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control. The investigators will address and attempt to answer two questions. (i) How do three nights of reduced sleep or a diagnosis of Insomnia Disorder affect the processing and regulation of emotional information compared to typical, undisturbed sleep? (ii) What overlapping and distinct neural mechanisms are engaged and associated with behavioral effects when attempting to process and regulate emotions in a sleep restricted state or with a clinical diagnosis of Insomnia Disorder? This study will investigate sleep's role in emotion processing and regulation. The findings will help further understanding of the role of sleep in healthy emotional functioning.

Sponsor: Beth Israel Deaconess Medical Center

You may qualify if…

  • willing and able to follow the protocol
  • willing and able to meet inclusion criteria for fMRI scanning
  • willing to refrain from alcohol and recreational drugs for the duration of the protocol
  • normal or corrected to normal vision is required

You may not qualify if…

  • left-handedness or ambidexterity
  • the use of any drugs that could affect either sleep or cognitive functioning (e.g., prescription sleeping pills or antidepressants)

Where it's recruiting

Source: ClinicalTrials.gov · NCT05393830 · last updated 2026-04-14

The Effect of Sleep Loss on Emotion Regulation · TrialPath