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RecruitingPeripheral Arterial Disease

Carnosine for Peripheral Arterial Disease Patients

Eligible age

50–80 yrs

Accepts

Men

Locations

1 state

Healthy volunteers

No

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About this study

Oral supplementation of L-carnosine will increase muscle carnosine, stabilize HIF1-alpha promote angiogenesis, and thus improve the functioning of lower extremities in PAD patients.

Sponsor: Shahid Baba

You may qualify if…

  • ✓ 1. Male subjects more than \>50 to \<80 years of age.
  • ✓ 2. White or African American race.
  • ✓ 3. English Speaking.
  • ✓ 4. ABI 0.4-\< 0.60
  • ✓ 5. Willing to comply with protocol requirements.
  • ✓ 6. Able to provide informed consent. -

You may not qualify if…

  • ✕ 1. Subjects with HIV, hepatitis, significant liver disease, active infection, anemia, organ transplant, renal disease requiring dialysis, lung disease requiring oxygen, significant congenital heart disease, cancer of any type, and untreated thyroid disease.
  • ✕ 2. Diagnosis of carnosinemia.
  • ✕ 3. Known allergy to L-carnosine or meat.
  • ✕ 4. Presence of a pacemaker.
  • ✕ 5. Obesity from a known genetic defect.
  • ✕ 6. Dementia.
  • ✕ 7. Critical limb ischemia with below or above knee amputations.
  • ✕ 8. Foot ulcers.

Where it's recruiting

Kentucky

Louisville

Source: ClinicalTrials.gov · NCT05371145 · last updated 2024-07-22

Carnosine for Peripheral Arterial Disease Patients · TrialPath