Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors
Eligible age
4–39 yrs
Accepts
All genders
Locations
3 states
Healthy volunteers
No
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About this study
This study will evaluate the safety and efficacy of Lutathera (177Lu-DOTATATE) in patients with progressive or recurrent High-Grade Central Nervous System (CNS) tumors and meningiomas that demonstrate uptake on DOTATATE PET. The drug will be given intravenously once every 8 weeks for a total of up to 4 doses over 8 months in patients aged 4 to \<12 years (Phase I) or 12 to \</=39 years (Phase II) to test its safety and efficacy, respectively. Funding Source - FDA OOPD (grant number FD-R-0532-01)
Sponsor: Nationwide Children's Hospital
Where it's recruiting
Source: ClinicalTrials.gov · NCT05278208 · last updated 2026-07-20