RecruitingSpinal Cord Injuries
Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury
Eligible age
21–70 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to assess the efficacy of non-invasive (transcutaneous) closed-loop electrical spinal cord stimulation for recovery of upper limb function (Aim 1) and spasticity (Aim 2) following spinal cord injury.
Sponsor: University of Washington
You may qualify if…
- ✓ 1. has cervical (C8 or higher), incomplete (American Spinal Cord Injury Impairment Scale - C or D) traumatic spinal cord injury, minimum 1-year post-injury
- ✓ 2. has difficulty with hand functions in activities of daily living (e.g., dressing, grooming, feeding)
- ✓ 3. stable medical condition without cardiopulmonary disease or autonomic dysreflexia that would contraindicate participation in upper extremity rehabilitation or testing activities
- ✓ 4. capable of performing simple cued motor tasks
- ✓ 5. has ability to attend intervention/functional task training and assessment sessions 3 times/week
- ✓ 6. has adequate social support to participate in all intervention and baseline/follow-up assessment sessions throughout 40 weeks.
- ✓ 7. has ability to read and speak English
You may not qualify if…
- ✕ 1. dependent on ventilation support
- ✕ 2. has implanted stimulator (e.g., pacemaker, vagus nerve stimulator, cochlear implant, etc.) or baclofen pump
- ✕ 3. has metallic devices and implants in the head (e.g., deep brain stimulators, aneurysm clips/coils, and stents, vagus nerve stimulators)
- ✕ 4. has a history or current signs/symptoms of syringomyelia (progressive pain, muscle weakness, and/or sensory loss; deterioration of bowel/bladder function)
- ✕ 5. has autoimmune etiology of spinal cord dysfunction/injury
- ✕ 6. has received botulinum toxin injections in upper extremity muscles in the prior 6 months
- ✕ 7. has tendon transfer or nerve transfer surgery in the upper extremity,
- ✕ 8. taking tizanidine, dantrolene or diazepam
Where it's recruiting
Washington
Seattle
Source: ClinicalTrials.gov · NCT05267951 · last updated 2025-03-05