RecruitingRelapsed Adult AMLPrimary Refractory Acute Myeloid LeukemiaHigh Risk Acute Myeloid Leukemia
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
Eligible age
18–120 yrs
Accepts
All genders
Locations
17 states
Healthy volunteers
Yes
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About this study
This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).
Sponsor: Massachusetts General Hospital
You may qualify if…
- ✓ Patient Inclusion Criteria
- ✓ Hospitalized patients (age ≥ 18 years) with high-risk AML defined as:
- ✓ Patients with new diagnosis ≥ 60 years of age
- ✓ An antecedent hematologic disorder
- ✓ Therapy related-disease
- ✓ Relapsed or primary refractory AML
- ✓ Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial.
- ✓ Caregiver Inclusion Criteria
You may not qualify if…
- ✕ \- Patient Exclusion Criteria
- ✕ Patients with a diagnosis of acute promyelocytic leukemia (APML)
- ✕ Patients with AML receiving supportive care alone
- ✕ Patients with psychiatric or cognitive conditions which the treating clinicians believe prohibits informed consent or compliance with study procedures
- ✕ Patients seen by a palliative care clinician (MD, DO, APP) during two previous hospitalizations in the six months prior to enrollment
- ✕ Patients expected to be discharged within 2 days
Where it's recruiting
Alabama
Birmingham
California
Stanford
Colorado
Denver
Florida
Miami · Tampa
Georgia
Atlanta
Illinois
Evanston
Indiana
Bloomington
Maryland
Baltimore
Massachusetts
Boston
Minnesota
Rochester
New York
Rochester
North Carolina
Chapel Hill · Durham
Source: ClinicalTrials.gov · NCT05237258 · last updated 2025-07-25