Music Therapy for Patients With Alzheimer's Disease
Eligible age
18–89 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD). 60 patients with MCI or mild dementia due to AD will receive two 30 minutes reminiscence-targeted virtual music therapy interventions per week for 8 weeks (a total of 16 sessions). Participants' (or supported by the study partner) self-reported and measurable outcomes including cognitive, anxiety, quality of life, and autobiographical memory will be assessed before and after the 8-week course of treatment. Blood-oxygenation level-dependent (BOLD) in functional magnetic resonance imaging (fMRI) will also be also measured before and after the 8-week course of treatment.
Sponsor: Johns Hopkins University
You may qualify if…
- ✓ Age 18-89
- ✓ Mild Cognitive Impairment (MoCA score: 18-25) or Early AD (MoCA score: 17-24)
You may not qualify if…
- ✕ Head trauma, traumatic brain injury, or concussion with loss of consciousness for \>2 minutes
- ✕ Claustrophobia incompatible with MRI scanning
- ✕ Medical device incompatible with MRI scanning (e.g. cardiac pacemaker, implanted cardiac defibrillator, aneurysm brain clip, inner ear implant)
- ✕ Prior history as a metal worker and/or certain metallic objects in the body
- ✕ Exclusion Criteria will be carefully determined by the MRI screening form.
Where it's recruiting
Baltimore
Source: ClinicalTrials.gov · NCT05151562 · last updated 2026-05-06