Biomarker of Diabetic Retinopathy
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.
Sponsor: Indiana University
You may qualify if…
- ✓ Ability to cooperate with imaging procedures.
- ✓ Health status: established type 2 diabetes
- ✓ No history of panretinal photocoagulation (PRP)
- ✓ No history of treatment with intravitreal agents for past 12 months
You may not qualify if…
- ✕ Previous or current malignancy
- ✕ Acute or chronic infection (HIV, hepatitis B or C, tuberculosis)
- ✕ Cerebral vascular accident or cerebral vascular procedure
- ✕ Current pregnancy
- ✕ History of organ transplantation
- ✕ Presence of a graft (to avoid any effect of the graft)
- ✕ History of previous vitrectomy
- ✕ Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.
Where it's recruiting
Carmel · Indianapolis
Source: ClinicalTrials.gov · NCT05079399 · last updated 2026-07-23