Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial
Eligible age
40–80 yrs
Accepts
Men
Locations
1 state
Healthy volunteers
No
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About this study
Shoulder tendon tears are a common cause of shoulder pain and disability and after surgery the repaired tendon often does not heal. In this pilot study, men with low sex hormone levels will be randomly assigned to receive sex hormone therapy or placebo pills while healing from tendon repair surgery in their shoulder. Sex hormone therapy increases sex hormone levels, and the investigators will test whether these increased sex hormone levels show promise in improving tendon healing and patient shoulder function and pain.
Sponsor: University of Utah
You may qualify if…
- ✓ 1. A plan for a primary rotator cuff repair
- ✓ 2. Male sex
- ✓ 3. \>1 cm tear width, full thickness supraspinatus/infraspinatus tear
You may not qualify if…
- ✕ 1. Active infection
- ✕ 2. Pre-operative testosterone supplementation
- ✕ 3. Known diagnosis of secondary testicular failure or testosterone deficiency
- ✕ 4. Medically unfit for operative intervention
- ✕ 5. Revision surgery
- ✕ 6. Unwillingness to participate in the study, including post-operative imaging
- ✕ 7. Inability to read or comprehend written instructions
- ✕ 8. Prisoner
Where it's recruiting
Salt Lake City
Source: ClinicalTrials.gov · NCT04944836 · last updated 2026-03-19