RecruitingMalignant Brain Glioma
Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors
Eligible age
Up to 21 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This trial studies how well spectroscopic magnetic resonance imaging (MRI) guided proton therapy works in assessing metabolic change in pediatric patients with brain tumors. The non-invasive imaging, such as spectroscopic MRI may help to map the differences in tumor metabolism compared to healthy tissue without injection of any contrast agent.
Sponsor: Emory University
You may qualify if…
- ✓ Pathologically diagnosed high-grade glioma (World Health Organization \[WHO\] grade 3-4). Patients with a radiographically diagnosed high-grade glioma may enroll prior to pathologic confirmation, but would be removed from study if pathology did not confirm the diagnosis of high-grade glioma.
- ✓ Primary tumor located within the supratentorial brain.
- ✓ Recommended to receive definitive radiation therapy.
- ✓ Able to receive MRI scans.
- ✓ Both males and females, and members of all races and ethnic groups are eligible for this trial.
You may not qualify if…
- ✕ Patients with pacemakers, non-titanium aneurysm clips, neurostimulators, cochlear implants, non-titanium metal in ocular structures, or other incompatible implants which makes MRI safety an issue are excluded.
- ✕ Patients that have any significant medical illnesses that in the investigator's opinion cannot be adequately tolerate MRI scan are excluded.
- ✕ Pathology demonstrated low-grade glioma or other benign or non-invasive brain tumor.
Where it's recruiting
Georgia
Atlanta
Source: ClinicalTrials.gov · NCT04908709 · last updated 2026-03-04