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RecruitingNAFLD

Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

Eligible age

12–18 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.

Sponsor: Yale University

You may qualify if…

  • Good general health, taking no medication on a chronic basis;
  • age 12 to 18 years, in puberty (girls and boys: Tanner stage II-V);
  • BMI \>85th for obese cohort;

You may not qualify if…

  • Baseline creatinine \>1.0 mg; pregnancy;
  • the presence of endocrinopathies (e.g. Cushing syndrome);
  • cardiac or pulmonary or other significant chronic illness;
  • adolescents with a psychiatric disorder or with substance abuse;
  • monogenic obesity syndromes;
  • use of drugs affecting intrahepatic fat content (e.g.; liraglutide, fish oil, etc.).

Where it's recruiting

Connecticut

New Haven

Source: ClinicalTrials.gov · NCT04634643 · last updated 2025-01-27