RecruitingSpinal Cord InjuriesUrinary Incontinence
Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries
Eligible age
18–70 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
The goal of this study is to determine whether administration of sildenafil will decrease urine leakage in patients with spinal cord injuries.
Sponsor: The University of Texas Medical Branch, Galveston
You may qualify if…
- ✓ Adults with spinal cord injury (SCI), 18-75 years of age, at the time of consent
- ✓ Have urinary incontinence (UI), with at least 3 leakage episodes/week
- ✓ Have urodynamics assessment on file with their provider in past 3 years. If no historical data on file, subject may complete prior to study visit 1.
- ✓ Willing and able to comply with study procedures
- ✓ Willing and able to provide written informed consent
You may not qualify if…
- ✕ In phone prescreen, delighted or pleased with current quality of life due to urinary symptoms.
- ✕ Indwelling catheter
- ✕ History of greater than 4 urinary tract infections per year
- ✕ Multiple sclerosis
- ✕ Significant heart, liver, kidney, pulmonary, blood, autoimmune or peripheral vascular disease
- ✕ Systolic blood pressure \<90 or \>170, diastolic blood pressure \<50 or \>110 after repeated evaluation with proper cuff. This range is the acceptable range stated in the prescribing information for sildenafil (\>90/50 and \<170/110)
- ✕ Active cancer
- ✕ HIV, Hepatitis B, or Hepatitis C
Where it's recruiting
Texas
College Station · Galveston
Source: ClinicalTrials.gov · NCT04565925 · last updated 2025-12-16