Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer
Eligible age
21–80 yrs
Accepts
Women
Locations
2 states
Healthy volunteers
No
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About this study
This study will compare the effects on cardiorespiratory fitness (CRF) of aerobic exercise in different amounts (number of minutes/session) over different periods of time (number of weeks). Aerobic exercise is physical activity of light-to-moderate intensity that uses the large muscle groups (muscles in your legs, buttocks, back, and chest) and can be performed for at least 10 minutes. The researchers will study the effects of different exercise programs on how well the study participants' bodies use oxygen, how well their heart pumps blood, how well their lungs function, and how healthy their blood vessels are.
Sponsor: Memorial Sloan Kettering Cancer Center
You may qualify if…
- ✓ Aged 21-80 years
- ✓ Female
- ✓ Surgically resected early stage (I-III) primary breast cancer
- ✓ Post-menopausal, defined as one of the following:
- ✓ Age ≥ 45 with no menses for at least 2 years
- ✓ Chemically and/or surgically induced menopause through ovarian suppression, as determined by the primary oncologist
- ✓ Estradiol level of ≤30 pg/mL
- ✓ An interval of at least one year, but no more than five years, following the full completion of definitive therapy for malignant disease. Definitive therapy is defined as:
You may not qualify if…
- ✕ Any of the following absolute contraindications to cardiopulmonary exercise testing:
- ✕ Acute myocardial infarction within 3-5 days of any planned study procedures
- ✕ Unstable angina
- ✕ Uncontrolled arrhythmia causing symptoms or hemodynamic compromise
- ✕ Recurrent syncope
- ✕ Active endocarditis
- ✕ Acute myocarditis or pericarditis
- ✕ Symptomatic severe aortic stenosis
Where it's recruiting
Hartford
New York
Source: ClinicalTrials.gov · NCT04458532 · last updated 2026-03-25