RecruitingBreast CancerEarly-stage Breast Cancer
SABER Study for Selected Early Stage Breast Cancer
Eligible age
50+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.
Sponsor: University of Miami
You may qualify if…
- ✓ 1. Female, ≥ 50 years of age.
- ✓ 2. Oncotype or MammaPrint diagnosis results are required prior to the start of treatment
- ✓ 3. Histologically confirmed invasive breast cancer.
- ✓ 4. Clinical stage T1N0M0.
- ✓ 5. Receptor status: Estrogen-Receptor (ER)/Progesterone-Receptor (PR) positive and Human Epidermal Growth Factor Receptor 2 (HER2) negative.
- ✓ 6. Unifocal breast cancer.
- ✓ 7. Eastern Cooperative Oncology Group (ECOG) 0, 1.
- ✓ 8. Ability to undergo MRI.
You may not qualify if…
- ✕ 1. Patients without histologically confirmed invasive breast cancer.
- ✕ 2. Patients without Oncotype or MammaPrint diagnosis results at the start of treatment.
- ✕ 3. Patients with metastatic disease.
- ✕ 4. ECOG 2, 3, 4.
- ✕ 5. Patients that are unable to undergo MRI.
- ✕ 6. Prior history of radiation to the chest.
- ✕ 7. History of collagenous disease (systemic lupus erythematosus, scleroderma, dermatomyositis).
- ✕ 8. Any serious medical or psychiatric illness/condition likely in the judgment of the Investigator(s) to interfere or limit compliance with study requirements/treatment.
Where it's recruiting
Florida
Miami
Source: ClinicalTrials.gov · NCT04360330 · last updated 2026-08-03